Communications Biology (May 2021)

Optical interferometry based micropipette aspiration provides real-time sub-nanometer spatial resolution

  • Massimiliano Berardi,
  • Kevin Bielawski,
  • Niek Rijnveld,
  • Grzegorz Gruca,
  • Hilde Aardema,
  • Leni van Tol,
  • Gijs Wuite,
  • B. Imran Akca

DOI
https://doi.org/10.1038/s42003-021-02121-1
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 7

Abstract

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Beradi et al. establish a micropipette aspiration platform which enables sensitive real-time viscoelastic measurements of soft biomaterials. They use it to characterize the rheological behavior of cells and soft materials at very small deformations, yielding consistent and reproducible values.