Zanco Journal of Pure and Applied Sciences (Jun 2025)

AYURVEDIC MEDICINAL PLANTS AND THEIR NEUROPROTECTIVE POTENTIAL IN ALZHEIMER'S DISEASE

  • Bargale Sushant Sukumar,
  • Shashirekha H K,
  • Neha Gadgil,
  • Akshar Kulkarni,
  • Harshal Tare

DOI
https://doi.org/10.21271/zjpas.37.3.1
Journal volume & issue
Vol. 37, no. 3

Abstract

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Alzheimer's Disease (AD) poses a substantial universal health challenge with limited effective treatment options. Ayurvedic medicinal herbs are being evaluated as prospective candidates for neuroprotection due to their diverse array of bioactive compounds and comprehensive therapeutic principles. This review compiles the latest information on Ayurvedic herbs. It examines their mechanisms of action, clinical effectiveness, safety profiles, and regulatory issues in the management of AD. Key findings highlight their potential to mitigate neuroinflammation, oxidative stress, and cognitive decline, offering insights into integrative approaches that synergize traditional wisdom with modern pharmacotherapy. Future research directions underscore the need for mechanistic studies, large-scale clinical trials, and personalized medicine strategies to optimize therapeutic outcomes in AD.

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