Emerging Infectious Diseases (Jul 2025)

Emerging Infections Network Survey of Screening for Cryptococcal Antigenemia, United States, 2024

  • Kaitlin Benedict,
  • Alexander Jordan,
  • Jeremy A.W. Gold,
  • Dallas J. Smith,
  • Tom Chiller,
  • Ian Hennessee,
  • Philip M. Polgreen,
  • Susan E. Beekmann

DOI
https://doi.org/10.3201/eid3107.250295
Journal volume & issue
Vol. 31, no. 7
pp. 1493 – 1495

Abstract

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We polled infectious disease specialists about cryptococcal antigen screening for patients initiating HIV antiretroviral therapy. Of 215 respondents, 33% reported typically obtaining screening for patients with CD4 counts <200 cells/mm3 and 63% for counts <100 CD4 cells/mm3. Uncertainty about cryptococcal antigen screening benefits and recommendations suggests opportunities for education and increased screening.

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