Optimization of KI as X-Ray Computed Microtomography Contrast Agents for Murine and Chicken Epidermal Tissues Applications

Abstract

X-ray computed tomography (CT) vastly used in many different applications in different fields such as materials science, medical science, entomology, anatomy, marine sciences. Since the X-ray is highly penetrable, 3D image of almost any material can be achieved by CT. The high quality image of the materials, which compose in different types of atoms, can easily be achieved. However, obtain the high quality images of the materials which has similar types of atoms or relatively soft structure becomes a problem. Scientists investigating the soft tissues such as flesh, muscle, cartilage or animals in soft structure suffer from this problem. At this point, staining procedures, treating materials with contrast agents help the researcher to enhance the image quality. In this work, optimisation of KI based staining to obtain enhanced image quality in CT imaging of murine and chicken dermal tissues were studied. Results indicate that overstaining or staining the tissues in less concentration significantly affects the quality of the obtained CT images.

Keywords

• computed tomography
• skin
• phase contrast imaging
• absorption imaging
• staining
• soft tissue
• bilgisayarlı tomografi
• deri
• faz kontrast görüntüleme
• soğurma temelli görüntüleme
• lekeleme
• yumuşak doku