Фармакокинетика и Фармакодинамика (Nov 2017)

The study of the effects of magnesium orotate on the model of primary generalized convulsions in rats

  • A. G. Kalacheva,
  • T. E. Bogacheva,
  • O. A. Gromova,
  • T. R. Grishina,
  • V. I. Demidov

Journal volume & issue
Vol. 0, no. 4
pp. 7 – 11

Abstract

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The effect of magnesium orotate on the model of primary generalized convulsions in the experiment was studied. The course of administration of magnesium orotate (preparation Magneter) at a dose of 0,06 g / kg of weight reduces the severity and duration of seizures caused by thiosemicarbazide, increases the survival of animals, has a neuroprotective effect, affecting various morphological structures. The drug Magnerot - the donor of magnesium, replenishing in the body the deficit caused by the convulsant.

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