Clinical Ophthalmology (Oct 2020)
Long-Term Effects of Botulinum Toxin in Large-Angle Infantile Esotropia
Abstract
Flavio Gioele Gallo,1 Carmen Plaitano,2 Paolo Esposito Veneruso,3 Adriano Magli1 1Department of Medicine and Surgery, University of Salerno, Salerno, Italy; 2Department of Ophthalmology, A.O.U. San Giovanni Di Dio e Ruggi d’Aragona-Scuola Medica Salernitana, Salerno, Italy; 3Division of Ophthalmology, University Hospital “Federico II”, Naples, ItalyCorrespondence: Flavio Gioele GalloDepartment of Medicine and Surgery, University of Salerno, Via Salvador Allende, 43, Baronissi, Salerno 84081, ItalyTel +39 3898535899Email [email protected]: The purpose of this study is the motor outcome analysis of early Botulinum toxin (BT) treatment in patients affected by large-angle infantile esotropia (IE).Patients and Methods: Retrospective analysis of 130 medical charts of IE patients who underwent BT injections between 2004 and 2019 was performed. All patients underwent BT injections within 13 months of age.Results: Thirty patients, matching the inclusion criteria, were included in the study. Twenty-eight patients showing residual ET ≥ 25 PD (34.3± 6.6 PD ranged from 25 to 50) underwent surgery.Conclusion: Our result after 1 Botulinum toxin injection showed a very low success rate (6.7%) at last follow-up (28.3± 7.2 months). Our data would suggest one Botulinum toxin injection in children affected by large-angle infantile esotropia allows a significant reduction of deviation but does not avoid the need for surgical treatment.Keywords: strabismus, pediatric, congenital
