Exploring the Pharmacological Potential of <i>Lithospermum officinale</i> L.: A Review of Phytochemicals and Ethnomedicinal Uses
Gulzhanat Barkizatova,
Aknur Turgumbayeva,
Kairat Zhakipbekov,
Kuralay Bekesheva,
Zhalgaskali Arystanov,
Tanagul Arystanova,
Farida Kayupova,
Klara Zhumalina,
Zhanat Toxanbayeva,
Aigul Ibragimova,
Olga Blinova,
Gulnara Utegenova,
Nurzhan Iztileu,
Zhanserik Shynykul
Affiliations
Gulzhanat Barkizatova
School of Pharmacy, S.D. Asfendiyarov Kazakh National Medical University, Tole Bi St. 94, Almaty 050000, Kazakhstan
Aknur Turgumbayeva
Higher School of Medicine, Al-Farabi Kazakh National University, Almaty 050040, Kazakhstan
Kairat Zhakipbekov
Department of Organization, Management and Economics of Pharmacy and Clinical Pharmacy, Asfendiyarov Kazakh National Medical University, Tole Bi St. 94, Almaty 050000, Kazakhstan
Kuralay Bekesheva
JSC “Scientific Centre for Anti-Infectious Drug”, Astana 010000, Kazakhstan
Zhalgaskali Arystanov
Department of Pharmaceutical Disciplines, Astana Medical University, Beibitshilik Street 49/A, Astana 010000, Kazakhstan
Tanagul Arystanova
Department of Pharmaceutical Disciplines, Astana Medical University, Beibitshilik Street 49/A, Astana 010000, Kazakhstan
Farida Kayupova
Department of Pharmacy, Kazakh-Russian Medical University, Abylai Khan St. 51/53, Almaty 050004, Kazakhstan
Klara Zhumalina
Department of Pharmacy, Kazakh-Russian Medical University, Abylai Khan St. 51/53, Almaty 050004, Kazakhstan
Zhanat Toxanbayeva
Department of Pharmacology, Pharmacotherapy and Clinical Pharmacology, South Kazakhstan Medical Academy, Al Farabi Sq. 1, Shymkent 160019, Kazakhstan
Aigul Ibragimova
Department of Pharmacology, Pharmacotherapy and Clinical Pharmacology, South Kazakhstan Medical Academy, Al Farabi Sq. 1, Shymkent 160019, Kazakhstan
Olga Blinova
Department of Organization and Management of Pharmaceutical Business, South Kazakhstan Medical Academy, Alfarabi Sq. 1, Shymkent 160000, Kazakhstan
Gulnara Utegenova
Department of Organization and Management of Pharmaceutical Business, South Kazakhstan Medical Academy, Alfarabi Sq. 1, Shymkent 160000, Kazakhstan
Nurzhan Iztileu
Department of Pharmaceutical Disciplines, Astana Medical University, Beibitshilik Street 49/A, Astana 010000, Kazakhstan
Zhanserik Shynykul
Higher School of Medicine, Al-Farabi Kazakh National University, Almaty 050040, Kazakhstan
Exploring phytochemicals from ethnomedicinal plants for pharmacological applications is a promising research area. By studying ethnomedicine, researchers can identify plants used for centuries to treat ailments and investigate their phytochemicals. Consequently, phytochemicals can be isolated, characterized, and tested for pharmacological activities, leading to new drug development. This research also helps preserve traditional knowledge and biodiversity. Lithospermum officinale L., found in Eurasia, Argentina (South), Colombia, and the United States, is valued for its medicinal properties, including anti-inflammatory, antioxidant, and antimicrobial effects. The current review emphasizes L. officinale L. as a significant reservoir of bioactive phytochemicals, with alkaloids, quinones, glucosides, phenolics, flavonoids, and lipids identified as the principal metabolites. It also unveils the unexplored potential of this plant for future research endeavors. Continued research on L. officinale L. can unlock its full potential, providing insights into its medicinal uses and contributing to biodiversity preservation.
