The Association between Coagulation and Atrial Fibrillation
Saira Rafaqat,
Sanja Gluscevic,
Dimitrios Patoulias,
Saima Sharif,
Aleksandra Klisic
Affiliations
Saira Rafaqat
Department of Zoology (Molecular Physiology), Lahore College for Women University, Lahore 54600, Punjab, Pakistan
Sanja Gluscevic
Department of Neurology, Clinical Center of Montenegro, 81000 Podgorica, Montenegro
Dimitrios Patoulias
Outpatient Department of Cardiometabolic Medicine, Second Department of Cardiology, Aristotle University of Thessaloniki, General Hospital “Hippokration”, 54642 Thessaloniki, Greece
Saima Sharif
Department of Zoology (Molecular Physiology), Lahore College for Women University, Lahore 54600, Punjab, Pakistan
Aleksandra Klisic
Faculty of Medicine, University of Montenegro, 81000 Podgorica, Montenegro
The existing literature highlights the presence of numerous coagulation factors and markers. Elevated levels of coagulation factors are associated with both existing and newly diagnosed cases of atrial fibrillation (AF). However, this article summarizes the role of coagulation in the pathogenesis of AF, which includes fibrinogen and fibrin, prothrombin, thrombomodulin, soluble urokinase plasminogen activator receptor, von Willebrand factor, P-selectin, D-dimer, plasminogen activator inhibitor-1, and platelet activation. Coagulation irregularities play a significant role in the pathogenesis of AF.
