Klinicheskie i biokhimicheskie aspekty issledovaniya insulinonodobnogo faktora rosta-1 v syvorotke krovi u retsipientov s narusheniyami kostnogo obmena posle peresadki serdtsa i pochki

Abstract

Insulin-like growth factor-1 (IGF-1), parathyroid hormone (PTH), biochemical markers of bone resorption and formation, bone mineral density (МПК) in spine and hip were determined in 46 recipients following heart transplantation (HI) and 79 -following kidney transplantation (KT) receiving triple immunosuppressive therapy. Serum IGF-1 in total recipients group (n=125) in mean was significantly lower then in health volunteers (187±102 and 250±51 ng/ml respectively; p