Periodontal Disease, Tooth Loss, and Systemic Conditions: An Exploratory Study

Georgios S. Chatzopoulos; Ziou Jiang; Nicholas Marka; Larry F. Wolff

International Dental Journal (Apr 2024)

Periodontal Disease, Tooth Loss, and Systemic Conditions: An Exploratory Study

Georgios S. Chatzopoulos,
Ziou Jiang,
Nicholas Marka,
Larry F. Wolff

Affiliations

Georgios S. Chatzopoulos: Division of Periodontology, Department of Developmental and Surgical Sciences, School of Dentistry, University of Minnesota, Minneapolis, Minnesota, USA; Department of Preventive Dentistry, Periodontology and Implant Biology, Faculty of Dentistry, School of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece; Corresponding author. Department of Developmental and Surgical Sciences, Division of Periodontology, School of Dentistry, University of Minnesota, 515 Delaware Street SE, Minneapolis, MN, 55455, USA.
Ziou Jiang: Biostatistical Design and Analysis Center, Clinical and Translational Science Institute, University of Minnesota, Minneapolis, Minnesota, USA
Nicholas Marka: Biostatistical Design and Analysis Center, Clinical and Translational Science Institute, University of Minnesota, Minneapolis, Minnesota, USA
Larry F. Wolff: Division of Periodontology, Department of Developmental and Surgical Sciences, School of Dentistry, University of Minnesota, Minneapolis, Minnesota, USA

Journal volume & issue: Vol. 74, no. 2
pp. 207 – 215

Abstract

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ABSTRACT: Background: Although systemic medical conditions are associated with periodontitis and tooth loss, large-scale studies that include less prevalent systemic conditions are needed. The purpose of the study was to investigate the link between periodontal disease and tooth loss with systemic medical conditions in a large and diverse population. Methods: Dental charts of adult patients who had attended the dental clinics seeking dental therapy of the universities contributing data to the BigMouth network and accepted the protocol of the study were included. Dental Procedure Codes and Current Procedural Terminology procedures were utilised to identify patients with and without periodontitis. Data were extracted from patients’ electronic health records including demographic characteristics, dental procedural codes, and self-reported medical conditions as well as the number of missing teeth. Results: A total of 108,307 records were ultimately included in the analysis; 42,377 of them included a diagnosis of periodontitis. The median age of the included population was 47.0 years, and 55.2% were female. Older and male individuals were significantly more likely to be in the periodontitis group and have higher number of missing teeth. A number of systemic conditions are associated with periodontitis and a higher number of missing teeth. High blood pressure, smoking, drug use, and diabetes were all found to be significant. Other significant conditions were anaemia, lymphoma, glaucoma, dialysis, bronchitis, sinusitis hepatitis, and asthma. Conclusions: Within the limitations of this retrospective study that utilised the BigMouth dental data repository, the association of a number of systemic conditions such as smoking, diabetes, and hypertension with periodontitis and tooth loss has been confirmed. Additional connections have been highlighted for conditions that are not commonly reported in the literature.

Published in International Dental Journal

ISSN: 0020-6539 (Print); 1875-595X (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Medicine: Dentistry
Website: https://www.journals.elsevier.com/international-dental-journal

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Abstract

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