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Coronavirus: a clinical update of Covid-19

Revista da Associação Médica Brasileira. 66(2):116-123 DOI 10.1590/1806-9282.66.2.116

 

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Journal Title: Revista da Associação Médica Brasileira

ISSN: 0104-4230 (Print); 1806-9282 (Online)

Publisher: Associação Médica Brasileira

LCC Subject Category: Medicine: Medicine (General)

Country of publisher: Brazil

Language of fulltext: English, Spanish, Portuguese

Full-text formats available: PDF, HTML, XML

 

AUTHORS


Mateus da Silveira Cespedes

José Carlos Rosa Pires de Souza

EDITORIAL INFORMATION

Peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 12 weeks

 

Abstract | Full Text

SUMMARY INTRODUCTION A covid-19 pandemic decreed by WHO has raised greater awareness of it. EPIDEMIOLOGY The infection reached the mark of 350,000 patients in 33 countries and affected as comorbidities the presence of comorbidities and advanced age. TRANSMISSIBILITY The transmissibility calculated so far is similar to the H1N1 epidemic, but with lower mortality rates. PHYSIOPATHOLOGY The SARS-CoV-2 virus, of the Coronaviridae family, has the capacity for cellular invasion through the angiotensin-converting enzyme 2 does not have a lower respiratory epithelium and in the cells of the small intestine mucosa. CLINICAL MANIFESTATIONS a presentation can be divided into mild (fever, fatigue, cough, myalgia, and sputum) and severe (cyanosis, dyspnoea, tachypnea, chest pain, hypoxemia and need for clinical measurement) and has an estimated estimate of 2%. DIAGNOSIS allows the detection of viral load in CRP-TR of patients with high clinical suspicion. TREATMENT based on supportive measures and infection control. In severe cases, the use of medications such as hydroxychloroquine and azithromycin or medication can be promising. Take care to avoid the use of corticosteroids. There are no restrictions on the use of resources and ACEIs / ARBs.