Genome-scale CRISPR–Cas9 screen reveals novel regulators of B7-H3 in tumor cells

• Hui Yang,
• Gang Guo,
• Min Mu,
• Xi Zheng,
• Yuelong Wang,
• Ting Cao,
• Shasha Zhao,
• Cheng Huang,
• Xin Tang,
• Guoqing Wang,
• Nian Yang,
• Zhiguo Wu,
• Hexian Li,
• Kunhong Zhong,
• Zongliang Zhang,
• Meijun Zheng,
• Chunlai Nie,
• Liangxue Zhou,
• Aiping Tong

Affiliations

Hui Yang

Key Laboratory of Non-coding RNA Transformation Research of Anhui Higher Education Institution (Wannan Medical College), Wuhu, China

Gang Guo

Aff1 grid.410427.40000000419370183Department of Biochemistry and Molecular BiologyGeorgia Regents University Augusta GA USA

Min Mu

2 Department of Public Health, School of Medicine, Anhui University of Science and Technology, Huainan, Anhui, China

Xi Zheng

1Second Affiliated Hospital, and the Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Zhejiang University College of Medicine, China

Yuelong Wang

Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China

Ting Cao

Lab of Infectious Diseases and Vaccine, West China Hospital, Sichuan University, Chengdu, Sichuan, China

Shasha Zhao

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, and Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu, Sichuan, China

Cheng Huang

1Department of Global Health, George Washington University, Washington, District of Columbia, USA

Xin Tang

Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China

Guoqing Wang

Department of Neurology, Bin zhou People`s Hospital, Binzhou, Shandong, China

Nian Yang

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, and Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu, Sichuan, China

Zhiguo Wu

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, and Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu, Sichuan, China

Hexian Li

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, and Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu, Sichuan, China

Kunhong Zhong

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, and Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu, Sichuan, China

Zongliang Zhang

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, and Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu, Sichuan, China

Meijun Zheng

Department of Otolaryngology, Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China

Chunlai Nie

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, and Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu, Sichuan, China

Liangxue Zhou

Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China

Aiping Tong

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, and Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu, Sichuan, China