ANTITHROMBOTIC PREVENTION IN WOMEN WITH MEDICAL HISTORY SIGNIFICANT FOR OBSTETRIC AND THROMBOTIC EVENTS. CLINICAL OBSERVATION

Abstract

The article presents a clinical case of management of pregnancy in a woman with medical history signficant for obstetric and thrombotic events. After a thorough examination of the hemostatic system the role of genetic and acquired thrombophilia was identified. From a modern point of view thrombophilia is considered to be the etiopathogenetic factor for a wide range of diseases and syndromes – fetal loss syndrome, preeclampsia, thromboembolic complications of hormonal contraception and hormonal replacement therapy. The role of anticoagulant and antiplatelet therapy is discussed, in particular the use of dipyridamole in obstetric practice.

Keywords

• dipyridamole
• bemiparin sodium
• thrombophilia
• antiphospholipid syndrome
• hyperhomocysteinemia
• ischemic stroke
• antenatal fetal death