PI-05: PHARMACODYNAMIC EFFECTS OF AG-946, A HIGHLY POTENT NOVEL ACTIVATOR OF PYRUVATE KINASE, IN EX VIVO TREATMENT OF RED BLOOD CELLS FROM SICKLE CELL DISEASE PATIENTS

• RAB M.,
• VAN DIJK M.,
• BOS J.,
• VAN OIRSCHOT B.,
• GERRITS J.,
• KOSINSKI P.,
• KUNG C.,
• JANS J.,
• VAN BEERS E.,
• DANG L.,
• VAN WIJK R.

Affiliations

RAB M.

1 UMC Utrecht, Utrecht University, 3584 CX Utrecht, NETHERLANDS

VAN DIJK M.

1 UMC Utrecht, Utrecht University, 3584 CX Utrecht, NETHERLANDS

BOS J.

1 UMC Utrecht, Utrecht University, 3584 CX Utrecht, NETHERLANDS

VAN OIRSCHOT B.

1 UMC Utrecht, Utrecht University, 3584 CX Utrecht, NETHERLANDS

GERRITS J.

1 UMC Utrecht, Utrecht University, 3584 CX Utrecht, NETHERLANDS

KOSINSKI P.

2 Agios Pharmaceuticals Inc, Cambridge, UNITED STATES

KUNG C.

2 Agios Pharmaceuticals Inc, Cambridge, UNITED STATES

JANS J.

1 UMC Utrecht, Utrecht University, 3584 CX Utrecht, NETHERLANDS

VAN BEERS E.

1 UMC Utrecht, Utrecht University, 3584 CX Utrecht, NETHERLANDS

DANG L.

2 Agios Pharmaceuticals Inc, Cambridge, UNITED STATES

VAN WIJK R.

1 UMC Utrecht, Utrecht University, 3584 CX Utrecht, NETHERLANDS