PET Criteria by Cancer Type from Imaging Interpretation to Treatment Response Assessment: Beyond FDG PET Score

Francesco Dondi; Achille Lazzarato; Joana Gorica; Priscilla Guglielmo; Francesca Borgia; Rossella Filice; Antonio Vento; Sara Pacella; Riccardo Camedda; Matteo Caracciolo; Maria Silvia De Feo; Paolo Mammucci; Viviana Frantellizzi; Naima Ortolan; Elisa Fiasconaro; Luca Urso; Laura Evangelista; Riccardo Laudicella; Giulia Santo

doi:10.3390/life13030611

Life (Feb 2023)

PET Criteria by Cancer Type from Imaging Interpretation to Treatment Response Assessment: Beyond FDG PET Score

Francesco Dondi,
Achille Lazzarato,
Joana Gorica,
Priscilla Guglielmo,
Francesca Borgia,
Rossella Filice,
Antonio Vento,
Sara Pacella,
Riccardo Camedda,
Matteo Caracciolo,
Maria Silvia De Feo,
Paolo Mammucci,
Viviana Frantellizzi,
Naima Ortolan,
Elisa Fiasconaro,
Luca Urso,
Laura Evangelista,
Riccardo Laudicella,
Giulia Santo

Affiliations

Francesco Dondi: Nuclear Medicine, ASST Spedali Civili di Brescia, 25123 Brescia, Italy
Achille Lazzarato: Unit of Nuclear Medicine, Department of Medicine, Surgery and Pharmacy, Università degli Studi di Sassari, 07100 Sassari, Italy
Joana Gorica: Department of Radiological Sciences, Oncology and Anatomo-Pathology, Sapienza, University of Rome, 00161 Rome, Italy
Priscilla Guglielmo: Nuclear Medicine Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy
Francesca Borgia: Nuclear Medicine Unit, Oncological Medical and Specialists Department, University Hospital of Ferrara, 44124 Ferrara, Italy
Rossella Filice: Nuclear Medicine Unit, University Hospital “Paolo Giaccone”, Via del Vespro 129, 90127 Palermo, Italy
Antonio Vento: Nuclear Medicine Department, ASP 1-P.O. San Giovanni di Dio, 92100 Agrigento, Italy
Sara Pacella: Nuclear Medicine Department, Fondazione IRCCS Ca’Granda, Ospedale Maggiore Policlinico, via Francesco Sforza 35, 20122 Milan, Italy
Riccardo Camedda: Department of Biomedicine and Prevention, University of Rome “Tor Vergata”, 00133 Rome, Italy
Matteo Caracciolo: Nuclear Medicine Unit, Oncological Medical and Specialists Department, University Hospital of Ferrara, 44124 Ferrara, Italy
Maria Silvia De Feo: Department of Radiological Sciences, Oncology and Anatomo-Pathology, Sapienza, University of Rome, 00161 Rome, Italy
Paolo Mammucci: Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Piazza Giulio Cesare 11, 70124 Bari, Italy
Viviana Frantellizzi: Department of Radiological Sciences, Oncology and Anatomo-Pathology, Sapienza, University of Rome, 00161 Rome, Italy
Naima Ortolan: Nuclear Medicine Unit, Oncological Medical and Specialists Department, University Hospital of Ferrara, 44124 Ferrara, Italy
Elisa Fiasconaro: Nuclear Medicine Unit, S. Antonio Abate Hospital, 54027 Trapani, Italy
Luca Urso: Nuclear Medicine Unit, Oncological Medical and Specialists Department, University Hospital of Ferrara, 44124 Ferrara, Italy
Laura Evangelista: Department of Medicine DIMED, University of Padua, 35128 Padua, Italy
Riccardo Laudicella: Nuclear Medicine Unit, S. Antonio Abate Hospital, 54027 Trapani, Italy
Giulia Santo: Department of Experimental and Clinical Medicine, “Magna Graecia” University of Catanzaro, 88100 Catanzaro, Italy

DOI: https://doi.org/10.3390/life13030611
Journal volume & issue: Vol. 13, no. 3
p. 611

Abstract

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Background: in recent years, the role of positron emission tomography (PET) and PET/computed tomography (PET/CT) has emerged as a reliable diagnostic tool in a wide variety of pathological conditions. This review aims to collect and review PET criteria developed for interpretation and treatment response assessment in cases of non-[18F]fluorodeoxyglucose ([18F]FDG) imaging in oncology. Methods: A wide literature search of the PubMed/MEDLINE, Scopus and Google Scholar databases was made to find relevant published articles about non-[18F]FDG PET response criteria. Results: The comprehensive computer literature search revealed 183 articles. On reviewing the titles and abstracts, 149 articles were excluded because the reported data were not within the field of interest. Finally, 34 articles were selected and retrieved in full-text versions. Conclusions: available criteria are a promising tool for the interpretation of non-FDG PET scans, but also to assess the response to therapy and therefore to predict the prognosis. However, oriented clinical trials are needed to clearly evaluate their impact on patient management.

Published in Life

ISSN: 2075-1729 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science
Website: http://www.mdpi.com/journal/life

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