Chiral Phosphoric Acid Diesters as Ligands in Asymmetric Transition Metal Catalyzed Hydrogenation

Abstract

A chiral phosphoric acid diester, specifically the BINOL-based derivative, has been used for the first time in Rh-, Ir-, and Pd-catalyzed hydrogenation of olefins and imines, giving ee-values of up to 85%.

Keywords

• Asymmetric catalysis
• Chirality
• Hydrogenation
• Iridium
• Palladium
• Phosphorus ligands