Clinical and functional features of gastroesophageal refl ux disease in children and adolescents

Abstract

The aim of our work was to study clinical and endoscopic peculiarities, infl uence of H.Pylori infection and gastric acidity on changes of mucosa of the esophagus in children and adolescents with gastroesophageal refl ux disease (GERD). 140 children (93 with GERD: 48.4% – children with oesophagitis, 51.6% – children with endoscopically negative form of GERD) were examinated. Main complaints of heartburn were in 79,6% patients. Frequency and intensity of heartburn did not depend on oesophagitis presence. The correlation between frequency and severity of heartburn and endoscopic changes wasn’t detected. Esophageal endoscopic changes were combined with moderate infl ammation signs of stomach and duodenum. The correlation between H.Pylori and GERD wasn’t detected. According to acidometry data hyperacid state in stomach prevailed.

Keywords

• heartburn
• gastroesophageal refl ux disease
• endoscopic changes
• H. рylori
• acidometry
• children and adolescents