Einstein (São Paulo) (Dec 2009)

Long-term follow-up of advanced bladder adenocarcinoma

  • Karen Korkes,
  • Marcela Presti,
  • Fernando Korkes,
  • Marilia Germanos Castro

Journal volume & issue
Vol. 7, no. 4
pp. 485 – 487

Abstract

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Objective: to evaluate patients treated with primary bladder adenocarcinoma at our institution. Methods: A review of 30 patients diagnosed with bladder adenocarcinoma at a single institution from 1994 of 2005 was undertaken. Cases of primary bladder adenocarcinoma were retrospectively evaluated. Rresults: Out of 490 patients with bladder carcinoma, 30 had bladder adenocarcinoma: 22 metastatic tumors, eight (1.6%) primary adenocarcinoma. Of these, three (0.6%) were primary non-urachal and five (1.0%) were urachal adenocarcinoma. All patients were men with mean age of 55.8 years (range 37-83). Dysuria and hematuria were the main symptoms reported. Of the total, four patients had cancer-related mortality. Cconclusion: Primary bladder adenocarcinoma is a rare neoplasm, observed in 1.6% patients with bladder malignancies. Late diagnosis limits therapeutic possibilities. Partial cystectomy seems to have unsatisfactory results and radical cystectomy, although remains as the gold standard, have no proven efficacy. New methods of adjuvant treatment must be studied to improve treatment outcomes, as high mortality is observed despite treatment.

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