Revista da Escola de Enfermagem da USP (Oct 2015)

Controlling wound odor with metronidazole: a systematic review

  • Diana Lima Villela de Castro,
  • Vera Lúcia Conceição de Gouveia Santos

DOI
https://doi.org/10.1590/S0080-623420150000500021
Journal volume & issue
Vol. 49, no. 5
pp. 858 – 863

Abstract

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AbstractOBJECTIVEVerifying the evidence of therapeutic efficacy in the topical application of metronidazole for controlling wound odor.METHODSA systematic literature review, according to the Cochrane Collaboration recommendations.RESULTS329 articles were identified in the Cochrane, LILACS, SciELO, CINAHL and PubMed databases, with 14 of them being included in the final sample. Two of the studies were double-blind randomized clinical trial studies.CONCLUSIONThe actual effectiveness of metronidazole in controlling wound odor cannot yet be evidenced due to the absence of strong evidence from studies on the subject, despite clinical practice recommending its benefits.

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