1006 High doses of MHC-II neoantigens in peptide cancer vaccines induce tumor-specific inhibitory cytolytic CD4+ T cells

• Naveen Sharma,
• James Allison,
• Andres Salazar,
• Hussein Sultan,
• Ton Schumacher,
• Ivana Djuretic,
• Yik Andy Yeung,
• Jeffrey Ward,
• Marco Colonna,
• Yuang Song,
• Samuel Ameh,
• Robert Schreiber,
• Kenneth Murphy,
• Yoshiko Takeuchi,
• Corazon Arthur,
• Kathleen Sheehan,
• Kelly D Moynihan,
• Vladimir Sukhov,
• Maria Firulyova,
• Tian-Tian Liu,
• Maxim Artyomov

Affiliations

Naveen Sharma

3Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, Houston, TX, USA

James Allison

Aff2 grid.240145.60000000122914776The University of Texas MD Anderson Cancer Center Houston TX USA

Andres Salazar

2Oncovir, Washington DC, United States

Hussein Sultan

Aff483 grid.410427.40000000122849329Augusta University, Georgia Cancer Center Augusta GA USA

Ton Schumacher

2The Netherlands Cancer Institute, Amsterdam, Netherlands

Ivana Djuretic

Aff1 Celgene Cellular Therapeutics Warren NJ USA

Yik Andy Yeung

Pfizer Cancer Immunology Discovery, Pfizer Inc, San Diego, California, USA

Jeffrey Ward

4Washington University, Saint Louis, MO, USA

Marco Colonna

6Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri, USA

Yuang Song

1Washington University School of Medicine, St. Louis, MO, USA

Samuel Ameh

1Washington University School of Medicine, St. Louis, MO, USA

Robert Schreiber

1Washington University School of Medicine, Saint Louis, MO, USA

Kenneth Murphy

1 Psychiatry, NHS Lothian, Edinburgh, UK

Yoshiko Takeuchi

1Washington University School of Medicine, Saint Louis, MO, United States

Corazon Arthur

1Washington University School of Medicine, Saint Louis, MO, USA

Kathleen Sheehan

Washington University in St. Louis, St Louis, MO, United States

Kelly D Moynihan

4Asher Biotherapeutics, Inc., South San Francisco, CA, USA

Vladimir Sukhov

1Washington University School of Medicine, St. Louis, MO, USA

Maria Firulyova

2Almazov National Medical Research Centre, St.Petersburg, St.Petersburg, Russian Federation

Tian-Tian Liu

1Washington University School of Medicine, Saint Louis, MO, USA

Maxim Artyomov

1Washington University School of Medicine, Saint Louis, MO, USA