Scientific Reports (Apr 2022)

Optimal cutoff values for physical function tests in elderly patients with heart failure

  • Keita Aida,
  • Kentaro Kamiya,
  • Nobuaki Hamazaki,
  • Kohei Nozaki,
  • Takafumi Ichikawa,
  • Takeshi Nakamura,
  • Masashi Yamashita,
  • Shota Uchida,
  • Emi Maekawa,
  • Jennifer L. Reed,
  • Minako Yamaoka-Tojo,
  • Atsuhiko Matsunaga,
  • Junya Ako

DOI
https://doi.org/10.1038/s41598-022-10622-0
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 9

Abstract

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Abstract Six-minute walk distance (6MWD) of 300 and 400 m are important targets of functional capacity. The present study was performed to determine cutoff values of physical function associated with 6MWD 65 years (median age, 75: interquartile range, 71–80, 607 men) with HF. 6MWD < 300 and < 400 m were seen in 323 patients (32.3%) and 658 patients (65.7%), respectively. Handgrip strength, QIS, OLST, and 5STS were associated with 6MWD < 300 and < 400 m, respectively (P < 0.001). The cutoff values of handgrip strength, QIS, OLST, and 5STS were 18.9 kg, 35.0% body mass (BM), 9.1 s, and 9.5 s for 6MWD < 300 m, and 21.9 kg, 40.0% BM, 12.0 s, and 8.8 s for < 400 m, respectively. The cutoff values of physical function could be used to set cardiac rehabilitation goals and limiting determinants of reduced functional capacity in a clinical setting in elderly patients with HF.