High-throughput microarray reveals the epitranscriptome-wide landscape of m6A-modified circRNA in oral squamous cell carcinoma
Wei Zhao,
Jingwen Liu,
Jie Wu,
Xiaozhou Ma,
Xi Wang,
Leyu Zhang,
Zhe Han,
Jianming Yang,
Yameng Cui,
Xin Hu,
Jiayin Deng
Affiliations
Wei Zhao
The School and Hospital of Stomatology, Tianjin Medical University
Jingwen Liu
The School and Hospital of Stomatology, Tianjin Medical University
Jie Wu
The School and Hospital of Stomatology, Tianjin Medical University
Xiaozhou Ma
The School and Hospital of Stomatology, Tianjin Medical University
Xi Wang
The School and Hospital of Stomatology, Tianjin Medical University
Leyu Zhang
The School and Hospital of Stomatology, Tianjin Medical University
Zhe Han
Institute of Orthopaedics, Tianjin Hospital
Jianming Yang
Department of Immunology, Key Laboratory of Immune Microenvironment and Disease of the Educational Ministry of China, Tianjin Key Laboratory of Cellular and Molecular Immunology, School of Basic Medical Sciences, Tianjin Medical University
Yameng Cui
Department of Integrated Traditional & Western Medicine, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer
Xin Hu
The School and Hospital of Stomatology, Tianjin Medical University
Jiayin Deng
The School and Hospital of Stomatology, Tianjin Medical University
Highlights 1. m6A-circRNAs exhibited their particular modification style in OSCC, which was independent of m6A-mRNA. 2. m6A on circRNAs frequently occurred on the long exons in the front part of CDS, which was distinct from m6A-mRNA that in 3’-UTR or stop codon.
