Progressive divisions of multipotent neural progenitors generate late-born chandelier cells in the neocortex

Abstract

Diverse GABAergic neurons arise from progenitors in the medial ganglionic eminence. Here, the authors show these progenitors are progressively fate-restricted, with early-born interneurons occupying cortex in an “inside-out” pattern and later-born types like chandelier cells generated “outside-in”.