Therapeutic potential of C1632 by inhibition of SARS-CoV-2 replication and viral-induced inflammation through upregulating let-7

• Chen Xie,
• Yanlian Chen,
• Dongling Luo,
• Zhen Zhuang,
• Heping Jin,
• Haoxian Zhou,
• Xiaocui Li,
• Haijun Lin,
• Xiaohui Zheng,
• Jing Zhang,
• Peihui Wang,
• Jincun Zhao,
• Yong Zhao,
• Hui Huang

Affiliations

Chen Xie

Key Laboratory of Gene Engineering of the Ministry of Education, School of Life Sciences, Sun Yat-sen University

Yanlian Chen

Key Laboratory of Gene Engineering of the Ministry of Education, School of Life Sciences, Sun Yat-sen University

Dongling Luo

Cardiovascular Department, The Eighth Affiliated Hospital, Sun Yat-sen University

Zhen Zhuang

State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University

Heping Jin

Key Laboratory of Gene Engineering of the Ministry of Education, School of Life Sciences, Sun Yat-sen University

Haoxian Zhou

Key Laboratory of Gene Engineering of the Ministry of Education, School of Life Sciences, Sun Yat-sen University

Xiaocui Li

Key Laboratory of Gene Engineering of the Ministry of Education, School of Life Sciences, Sun Yat-sen University

Haijun Lin

Xiamen Innodx Biotech Co., Ltd.

Xiaohui Zheng

School of Pharmaceutical Sciences, Wenzhou Medical University

Jing Zhang

Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University

Peihui Wang

Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University

Jincun Zhao

State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University

Yong Zhao

Key Laboratory of Gene Engineering of the Ministry of Education, School of Life Sciences, Sun Yat-sen University

Hui Huang

Cardiovascular Department, The Eighth Affiliated Hospital, Sun Yat-sen University