Primary large cell neuroendocrine carcinoma of the distal ureter: A rare entity

Abstract

Large cell neuroendocrine carcinoma (LCNEC) of the ureter is an extremely rare entity. Herein, we present a case of primary LCNEC of the distal ureter in an 80-year-old male with a history of intermittent hematuria and a mass in the right distal ureter on computed tomography of the abdomen and pelvis. The patient subsequently underwent surgery followed by adjuvant chemotherapy. Histology and immunohistochemistry were in accordance with LCNEC.

Keywords

• Ureter
• Neuroendocrine
• Urothelial carcinoma
• Immunohistochemistry