Journal of the International Association of Providers of AIDS Care (Jul 2017)

Normal CD4 Count Range among Healthy Nigerian Population in Ilorin

  • J. K. Afolabi FMCPAED,
  • A. Fadeyi FMCPATH,
  • O. O. Desalu FMCPATH,
  • I. A. Durotoye FMC,
  • A. E. Fawibe FMCP,
  • M. A. N. Adeboye FMCPAED,
  • H. O. Olawumi FWAP,
  • A. S. Babatunde FMCPATH,
  • S. K. Ernest FWACP,
  • S. A. Aderibigbe FWCP,
  • R. Saadu FMCOG,
  • A. K. Salami FWACP,
  • A. P. Aboyeji FWACS

DOI
https://doi.org/10.1177/2325957414530472
Journal volume & issue
Vol. 16

Abstract

Read online

Background: For the establishment and monitoring of the immune status, CD4 count is critical. Objectives: To determine the CD4 count range of apparently healthy Nigerians resident in Ilorin and compare with the national value. Methods: An automated blood analyzer was used to determine the full blood count and CD4 count. The percentage of CD4 count was derived by using other variables. Results: Of the 1205 participants, the reference CD4 count (percentage of CD4) range for adult was 400 to 1288 cells/mm 3 (19%-48%) and for children was 582 to 3652 cells/mm 3 (17%-50%). CD4 count and percentage of CD4 were significantly ( P = .001) higher in females than in males, and the CD4 count declined significantly with increasing age ( r = −.174, P ≤ .0001). The percentage of CD4 count shows less variation with age ( r = −.051, P = .076). Adult residents of Ilorin had significantly lower absolute mean CD4 count (808 ± 260) than that of the national reference values of 847.0 ± 307.0 cells/mm 3 ( P = .001). Conclusion: We therefore advocate the use of CD4 count range derived in this study is lower than that of the national reference values.