628 Circulatory plasma proteomic biomarkers combined with high-throughput proteomic screen of patient-derived organotypic tumor spheroids predict responses to immunotherapy in melanoma patients

• Yi Sun,
• Nir Hacohen,
• Keith Flaherty,
• Ryan Sullivan,
• Michelle Kim,
• Gyulnara Kasumova,
• Dennie Frederick,
• Michael Förster,
• Genevieve M Boland,
• Ryan Park,
• Marijana Rucevic,
• Arnav Mehta,
• Alexis Schneider,
• Russell W Jenkins,
• William Michaud,
• Benchun Miao,
• Or-Yam Revach,
• Angelina Cicerchia,
• Amrita Kar

Affiliations

Yi Sun

1 Department of Neurology, The First Affiliated Hospital of Wannan Medical College, Wuhu, China

Nir Hacohen

1Broad Institute of MIT and Harvard, Cambridge MA, USA

Keith Flaherty

3Massachusetts General Hospital, Boston, MA, USA

Ryan Sullivan

1Harvard Medical School, Boston, MA, USA

Michelle Kim

Department of Surgical Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

Gyulnara Kasumova

Department of Surgical Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

Dennie Frederick

Department of Surgical Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

Michael Förster

11Olink Proteomics, Waltham, MA, USA

Genevieve M Boland

Division of Surgical Oncology, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

Ryan Park

8Broad Institute of MIT and Harvard, Boston, USA

Marijana Rucevic

1Olink Proteomics, Boston, MA, USA

Arnav Mehta

7Massachusetts General Hospital, Boston, MA, USA

Alexis Schneider

6Broad Institute, Cambridge, MA, USA

Russell W Jenkins

2Massachusetts General Hospital, Boston, MA, USA

William Michaud

7Massachusetts General Hospital, Boston, MA, USA

Benchun Miao

2Massachusetts General Hospital, Boston, MA, USA

Or-Yam Revach

1Massachusetts General Hospital, Cambridge, MA, USA

Angelina Cicerchia

2Mass General Hospital Cancer Center, Massachusetts General Hospital Boston, MA, USA

Amrita Kar

4Olink Proteomics, Waltham, MA, USA