The Role of Topical Finasteride in Hair Loss Management: Current Evidence and Future Perspectives

Abstract

Hair loss (HL), scientifically known as alopecia, is a prevalent condition affecting individuals globally. Its multifactorial origins encompass genetics, hormonal fluctuations, stress, aging, medical conditions, and medications. The psychological impact of HL on self-esteem, confidence, and overall quality of life has driven the pursuit of effective treatments to rejuvenate hair growth and appearance. Among these treatments, finasteride (FIN) has been employed to address male pattern HL, the most prevalent form of HL in men. This medication hinders the conversion of testosterone to dihydrotestosterone (DHT), a hormone that contributes to hair follicle shrinkage and cessation of hair production. While oral FIN has been widely explored, it entails undesirable side effects and varying effectiveness. This review delves into the role of FIN topical applications as a novel approach for HL treatment.

Keywords

• hair loss
• hair follicle
• finasteride
• dihydrotestosterone