Advances in Animal Models and Evaluation Methods of Pain and Depression Comorbidity

Abstract

Comorbidity of pain and depression is a common health problem that seriously affects the physical and psychological health of patients. However, the pathogenesis of these symptoms remains unclear. To comprehensively understand the mechanisms and treatments of pain and depression comorbidity, this review summarizes the establishment of related animal models and behavioral evaluation methods of pain and depression comorbidity at home and abroad.

Keywords

• comorbid pain
• depression
• animal model
• evaluation