Recent advancement and development of chitin and chitosan-based nanocomposite for drug delivery: Critical approach to clinical research

Awais Ahmad; N.M Mubharak; Khalida Naseem; Hina Tabassum; Muhammad Rizwan; Agnieszka Najda; M. Kashif; May Bin-Jumah; Afzal Hussain; Asma Shaheen; Mohamed M. Abdel-Daim; Shafaqat Ali; Shahid Hussain

Arabian Journal of Chemistry (Dec 2020)

Recent advancement and development of chitin and chitosan-based nanocomposite for drug delivery: Critical approach to clinical research

Awais Ahmad,
N.M Mubharak,
Khalida Naseem,
Hina Tabassum,
Muhammad Rizwan,
Agnieszka Najda,
M. Kashif,
May Bin-Jumah,
Afzal Hussain,
Asma Shaheen,
Mohamed M. Abdel-Daim,
Shafaqat Ali,
Shahid Hussain

Affiliations

Awais Ahmad: Department of Chemistry, The University of Lahore, 54590 Lahore, Pakistan
N.M Mubharak: Department of Chemical Engineering, Faculty of Engineering and Science, Curtin University, 98009 Sarawak, Malaysia
Khalida Naseem: Department of Chemistry, Faculty of Sciences, University of Central Punjab, Lahore 54000, Pakistan
Hina Tabassum: Department of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan
Muhammad Rizwan: Department of Environmental Science and Engineering, Government College University, Faisalabad 38000, Pakistan
Agnieszka Najda: Laboratory of Quality of Vegetables and Medicinal Plants, Department of Vegetable Crops and Medicinal Plants, University of Life Sciences in Lublin, 15 Akademicka Street, 20-950 Lublin, Poland; Corresponding authors at: Department of Environmental Science and Engineering, Government College University, Faisalabad 38000, Pakistan (S. Ali). Laboratory of Quality of Vegetables and Medicinal Plants Department of Vegetable Crops and Medicinal Plants, University of Life Sciences in Lublin, 15 Akademicka Street, 20-950 Lublin, Poland (A. Najda). Pharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt (Abdel-Daim M.).
M. Kashif: School of Electrical and Information Engineering, Tianjin University, 92 Weijin Road, Nankai District, Tianjin 300072, China
May Bin-Jumah: Biology Department, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia
Afzal Hussain: Department of Environmental Science and Engineering, Government College University, Faisalabad 38000, Pakistan; Department of Environmental Science, The University of Lahore, Lahore 54590, Pakistan
Asma Shaheen: Department of Earth Sciences, University of Sargodha, 40100 Sargodha, Pakistan
Mohamed M. Abdel-Daim: Department of Zoology, Science College, King Saud University, Riyadh 11451, Saudi Arabia; Pharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt
Shafaqat Ali: Department of Environmental Science and Engineering, Government College University, Faisalabad 38000, Pakistan; Department of Biological Sciences and Technology, China Medical University (CMU), Taiwan; Corresponding authors at: Department of Environmental Science and Engineering, Government College University, Faisalabad 38000, Pakistan (S. Ali). Laboratory of Quality of Vegetables and Medicinal Plants Department of Vegetable Crops and Medicinal Plants, University of Life Sciences in Lublin, 15 Akademicka Street, 20-950 Lublin, Poland (A. Najda). Pharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt (Abdel-Daim M.).
Shahid Hussain: School of Materials Science and Engineering, Jiangsu University, Zhenjiang 212013, China; Corresponding authors at: Department of Environmental Science and Engineering, Government College University, Faisalabad 38000, Pakistan (S. Ali). Laboratory of Quality of Vegetables and Medicinal Plants Department of Vegetable Crops and Medicinal Plants, University of Life Sciences in Lublin, 15 Akademicka Street, 20-950 Lublin, Poland (A. Najda). Pharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt (Abdel-Daim M.).

Journal volume & issue: Vol. 13, no. 12
pp. 8935 – 8964

Abstract

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This review depicts the exposure of chitin and chitosan base multifunctional nanomaterial composites for promising applications in field of biomedical science structure, synthesis as well as potential application from a colossal angle. We elaborated critically each of the chitin and chitosan base nanomaterial with its potential application toward biomedical science. For different biomedical applications it use in form of hydrogels, microsphere, nanoparticles, aerogels, microsphere and in form of scaffold. Due to this it had been blended with different polymer such as starch, cellulose, alginate, lipid, hyaluronic acid, polyvinyl alcohol and caboxymethyl cellulose. In this review article, a comprehensive overview of combination of chitin and chitosan base nanomaterial with natural as well as synthetic polymers and their biomedical applications in biomedical field involving drug delivery system all the technical scientific issues have been addressed; highlighting the recent advancements.

Published in Arabian Journal of Chemistry

ISSN: 1878-5352 (Print)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Chemistry
Website: http://www.journals.elsevier.com/arabian-journal-of-chemistry/

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