XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53-mediated caspase-dependent apoptosis

• Eline Boons,
• Tatiane C. Nogueira,
• Tim Dierckx,
• Soraya Maria Menezes,
• Maarten Jacquemyn,
• Sharon Tamir,
• Yosef Landesman,
• Lourdes Farré,
• Achiléa Bittencourt,
• Keisuke Kataoka,
• Seishi Ogawa,
• Robert Snoeck,
• Graciela Andrei,
• Johan Van Weyenbergh,
• Dirk Daelemans

Affiliations

Eline Boons

KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute

Tatiane C. Nogueira

KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute

Tim Dierckx

KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical and Epidemiological Virology, Rega Institute

Soraya Maria Menezes

KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical and Epidemiological Virology, Rega Institute

Maarten Jacquemyn

KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute

Sharon Tamir

Karyopharm Therapeutics

Yosef Landesman

Karyopharm Therapeutics

Lourdes Farré

Instituto de Pesquisa Goncalo Moniz, Oswaldo Cruz Foundation (FIOCRUZ)

Achiléa Bittencourt

HUPES, Federal University of Bahia (UFBA)

Keisuke Kataoka

Department of Pathology and Tumor Biology, Kyoto University

Seishi Ogawa

Department of Pathology and Tumor Biology, Kyoto University

Robert Snoeck

KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute

Graciela Andrei

KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute

Johan Van Weyenbergh

KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical and Epidemiological Virology, Rega Institute

Dirk Daelemans

KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute