Nature Communications (Aug 2022)

Control cell migration by engineering integrin ligand assembly

  • Xunwu Hu,
  • Sona Rani Roy,
  • Chengzhi Jin,
  • Guanying Li,
  • Qizheng Zhang,
  • Natsuko Asano,
  • Shunsuke Asahina,
  • Tomoko Kajiwara,
  • Atsushi Takahara,
  • Bolu Feng,
  • Kazuhiro Aoki,
  • Chenjie Xu,
  • Ye Zhang

DOI
https://doi.org/10.1038/s41467-022-32686-2
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 13

Abstract

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Engineering peptide assembly that controls integrin ligand presentation on the molecular level possesses by far the highest ligand density, expanding the perspective of ligand-density-dependent modulation.