Diagnostic Challenges of Traumatic Ulcerative Granuloma with Stromal Eosinophilia in the Hard Palate
Giacomo Setti,
Stefania Caramaschi,
Giuseppe Barile,
Antonio d’Amati,
Marta Forte,
Giuseppe D’Albis,
Pierantonio Bellini,
Giovanna Garuti,
Luisa Limongelli,
Saverio Capodiferro
Affiliations
Giacomo Setti
Dentistry and Oral-Maxillofacial Surgery, Department of Surgical, Medical, Dental, and Morphological Science, University of Modena and Reggio Emilia, Via Del Pozzo 71, 41125 Modena, Italy
Stefania Caramaschi
Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Via Del Pozzo 71, 41125 Modena, Italy
Giuseppe Barile
Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70121 Bari, Italy
Antonio d’Amati
Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari “Aldo Moro”, 70100 Bari, Italy
Marta Forte
Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70121 Bari, Italy
Giuseppe D’Albis
Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70121 Bari, Italy
Pierantonio Bellini
Dentistry and Oral-Maxillofacial Surgery, Department of Surgical, Medical, Dental, and Morphological Science, University of Modena and Reggio Emilia, Via Del Pozzo 71, 41125 Modena, Italy
Giovanna Garuti
Dentistry and Oral-Maxillofacial Surgery, Department of Surgical, Medical, Dental, and Morphological Science, University of Modena and Reggio Emilia, Via Del Pozzo 71, 41125 Modena, Italy
Luisa Limongelli
Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70121 Bari, Italy
Saverio Capodiferro
Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70121 Bari, Italy
Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a benign lesion that may arise from the oral mucosa consisting in an ulcerative lesion usually localized in the tongue or cheek. Palate localization is very rare. Background/Objectives: The aim of this study is to describe a case of TUGSE occurring in the hard palate of an 83 y.o. female patient, manifesting as a non-painful growing palatal lesion approximately of 3.5 × 2 cm with firm consistency and a central area of erosion and erythema, the difficulties in clinical diagnosis, and the criteria for the differential diagnosis. Also, considering the rare occurrence of TUGSE in the palate, we performed a review of the literature too. Methods: A comprehensive review of the literature was conducted following the 2020 PRISMA guidelines and a total of seven records were identified as matching the inclusion criteria of this study. Results Conclusions: Although TUGSE is a benign lesion, the clinical presentation as a proliferative and ulcerative lesion may be challenging for clinicians mainly when arising in rare sites of occurrence (e.g., the hard palate).
