THE PROBLEMS OF EARLY DETECTION OF TUBERCULOSIS COMBINED WITH HIV INFECTION IN MODERN ECONOMIC CONDITIONS OF THE REPUBLIC OF TAJIKISTAN

Abstract

Objective: To study methods of early detection of TB diagnosis, morbidity, and prevalence of combined infection of TB/HIV and mortality from TB among HIV-infected patients. Methods: The analysis of the detection, prevalence and mortality from tuberculosis among HIV-infected patients carried out according to official report data of the Republican Center for Protection of the Population from Tuberculosis for 2005-2017 years. Results: Reach people living with HIV (PLHIV) to detect (TB) in them remains at a low level despite the increase in this indicator from 18% in 2006 to 56% in 2017. The TB incidence rate in Tajikistan in 2007-2008 was 85.1-85.2 cases per 100 thousand of the population and in 2015-2016 it decreased to 60.6-58.6 cases per 100 thousand of the population. Prevalence rates of HIV infection in 2007-2008 amounted to 15.5-20.1 cases per 100 thousand of the population, and in 2015-2016 it increased to 106.0-115.1 per 100 thousand of the population, i.е. marked its growth by 15.1 times. The prevalence of combined infection of TB/HIV in Tajikistan in 2006 was only 12 cases, and in 2016, it reached 1227, an increase of 102 times. The lethality among PLHIV from TB in 2006 was 41.4%; in the future, it increased annually and in 2011 reached 71.2% of the total number of PLHIV. Subsequent years, this indicator gradually decreased to 45% in 2016 (reaching 26.2%). Conclusion: The obtained results testify that the detection and diagnostics of TB among HIV-infected persons in Tajikistan carried out in the modern level. The prevalence of TB/HIV remains tense. The mortality rate among PLHIV from TB for 2006-2016 decreased from 71.2% to 45%, i.e. by 26.2%.

Keywords

• tuberculosis
• prevalence
• tb/hiv combined infection
• mortality.