Beneficial Impact of Vaccination Against SARS-CoV-2 on the Mental Health of IPF Patients

Ioannis Tomos; Andriana I. Papaioannou; Zoe I. Daniil; Ilias E. Dimeas; Paraskevi Kirgou; Athena Gogali; Konstantinos Tatsis; Ilias Papanikolaou; Vasilios Tzilas; Argyrios Tzouvelekis; Panayiota Tsiri; Paschalis Steiropoulos; Pachalis Ntolios; Areti Xyfteri; Katerina Antoniou; Emmanouil Symvoulakis; Aggeliki Haritou; Maria Maniati; Lykourgos Kolilekas; Elvira-Markella Antonogiannaki; Vasiliki Apollonatou; Maria Kallieri; Kostas Samaras; Stylianos Loukides; Anna Karakatsani; Demosthenes Bouros; Effrosyni Manali; Spyros Papiris

doi:10.3390/arm92060042

Advances in Respiratory Medicine (Nov 2024)

Beneficial Impact of Vaccination Against SARS-CoV-2 on the Mental Health of IPF Patients

Ioannis Tomos,
Andriana I. Papaioannou,
Zoe I. Daniil,
Ilias E. Dimeas,
Paraskevi Kirgou,
Athena Gogali,
Konstantinos Tatsis,
Ilias Papanikolaou,
Vasilios Tzilas,
Argyrios Tzouvelekis,
Panayiota Tsiri,
Paschalis Steiropoulos,
Pachalis Ntolios,
Areti Xyfteri,
Katerina Antoniou,
Emmanouil Symvoulakis,
Aggeliki Haritou,
Maria Maniati,
Lykourgos Kolilekas,
Elvira-Markella Antonogiannaki,
Vasiliki Apollonatou,
Maria Kallieri,
Kostas Samaras,
Stylianos Loukides,
Anna Karakatsani,
Demosthenes Bouros,
Effrosyni Manali,
Spyros Papiris

Affiliations

Ioannis Tomos: 5th Pulmonary Medicine Department, SOTIRIA Thoracic Diseases Hospital of Athens, 11527 Athens, Greece
Andriana I. Papaioannou: First Academic Department of Pneumonology, SOTIRIA Thoracic Diseases Hospital of Athens, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece
Zoe I. Daniil: Department of Respiratory Medicine, Medical School, University of Thessaly, 41110 Larissa, Greece
Ilias E. Dimeas: Department of Respiratory Medicine, Medical School, University of Thessaly, 41110 Larissa, Greece
Paraskevi Kirgou: Department of Respiratory Medicine, Medical School, University of Thessaly, 41110 Larissa, Greece
Athena Gogali: Department of Pneumonology, Medical School, University of Ioannina, 45500 Ioannina, Greece
Konstantinos Tatsis: Department of Pneumonology, Medical School, University of Ioannina, 45500 Ioannina, Greece
Ilias Papanikolaou: Pulmonary Department, Corfu General Hospital, 49100 Corfu, Greece
Vasilios Tzilas: 2nd Pulmonary Medicine Department, General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece
Argyrios Tzouvelekis: Department of Respiratory Medicine, General Hospital of Patras, University of Patras, 26500 Patras, Greece
Panayiota Tsiri: Department of Respiratory Medicine, General Hospital of Patras, University of Patras, 26500 Patras, Greece
Paschalis Steiropoulos: Department of Pneumonology, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, 68100 Alexandroupolis, Greece
Pachalis Ntolios: Department of Pneumonology, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, 68100 Alexandroupolis, Greece
Areti Xyfteri: Private Practice, 24200 Messini, Greece
Katerina Antoniou: Department of Thoracic Medicine and Laboratory of Molecular and Cellular Pneumonology, Medical School, University of Crete, 71500 Heraklion, Greece
Emmanouil Symvoulakis: Clinic of Social and Family Medicine, Department of Social Medicine, School of Medicine, University of Crete, 71500 Heraklion, Greece
Aggeliki Haritou: Private Practice, 45500 Ioannina, Greece
Maria Maniati: Private Practice, 45500 Ioannina, Greece
Lykourgos Kolilekas: 7th Pulmonary Department, SOTIRIA Thoracic Diseases Hospital of Athens, 15772 Athens, Greece
Elvira-Markella Antonogiannaki: 2nd Pulmonary Medicine Department, General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece
Vasiliki Apollonatou: 2nd Pulmonary Medicine Department, General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece
Maria Kallieri: 2nd Pulmonary Medicine Department, General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece
Kostas Samaras: Private Practice, 11527 Athens, Greece
Stylianos Loukides: 2nd Pulmonary Medicine Department, General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece
Anna Karakatsani: 2nd Pulmonary Medicine Department, General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece
Demosthenes Bouros: Iatriko Medical Center and National and Kapodstrian University of Athens, 15125 Athens, Greece
Effrosyni Manali: 2nd Pulmonary Medicine Department, General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece
Spyros Papiris: 2nd Pulmonary Medicine Department, General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece

DOI: https://doi.org/10.3390/arm92060042
Journal volume & issue: Vol. 92, no. 6
pp. 466 – 471

Abstract

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Background: Depression and anxiety represent significant comorbidities in idiopathic pulmonary fibrosis (IPF) patients, affecting their quality of life. The COVID-19 pandemic has had an uneven impact on global mental health. The Hospital Anxiety and Depression Scale (HADS) constitutes a validated tool to identify anxiety disorders and depression. The aim of this multicentre study was to evaluate the effect of COVID-19 vaccination on depression and anxiety in IPF patients. Methods: Consecutive IPF patients (median 73.5 years) who are regularly followed-up with were included in the study. Demographics, functional, and clinical were recorded. The HADS score was calculated before and one month after vaccination against COVID-19 in all participants. A Wilcoxon signed ranks test was conducted. Results: A total of 180 IPF patients (median 73.5 years) were included in the study. Among them, 145 patients (81%) received antifibrotic treatment. A significant reduction in HADS, both in anxiety and depression scales, was observed one month after vaccination against SARS-COV-2), independent of age, smoking, lung function impairment, and prior history of depression (p Conclusions: A higher Hospital Anxiety and Depression Scale score was detected before vaccination against COVID-19. It seems that vaccination also offered a beneficial effect on depression and anxiety in IPF patients, independent of age, smoking, lung function impairment, and prior history of depression.

Published in Advances in Respiratory Medicine

ISSN: 2451-4934 (Print); 2543-6031 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system; Medicine: Medicine (General)
Website: https://www.mdpi.com/journal/arm

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