Fertility & Reproduction (Dec 2023)

#159 : Aneuploidy Embryos Rate in Good Prognosis Patients After Fertilization Using ICSI and IMSI Methods

  • Reza Raharjo,
  • Arief Boediono,
  • Ivan Sini,
  • Wahyu Indrasari

DOI
https://doi.org/10.1142/S2661318223742443
Journal volume & issue
Vol. 05, no. 04
pp. 468 – 469

Abstract

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Background and Aims: Embryo aneuploidy is caused by many factors, including patient age, sperm quality and sperm selection method. There are several methods for selecting sperm, ICSI (intracytoplasmic sperm injection) and IMSI (intracytoplasmic morphologically selected sperm injection). Previous study related to the effect of sperm selection methods on aneuploidy embryos rate is still very rare. This study aims to determine the effect of selecting sperm methods on the aneuploidy embryos rate, especially in the good prognosis patient group. Method: A total of 67 patients with a good prognosis (AFCs[Formula: see text]6; AMH[Formula: see text]1,2) were grouped based on the method of selecting sperm. Furthermore, the fertilized oocytes that become blastocyst embryos were biopsied in the trophectoderm of the cell and compared between the two treatments. Results: The results of the study showed that the sperm selection method did not significantly affect the aneuploidy embryos rate (P>0.05). The percentage of aneuploidy embryos in the ICSI method was 28.1%, while in the IMSI method it was 24.3%. Conclusion: The conclusion of this study is that the sperm selection method does not affect the aneuploidy embryos rate in patients with a good prognosis.

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