Emerging treatment strategies for pulmonary fibrosis in precision medicine

Abstract

Pulmonary fibrosis （PF） is a chronic progressive lung disease that poses a serious health risk. It is mainly characterized by abnormal fibrosis and scarring of lung tissues， resulting in the gradual replacement of alveoli with fibrous tissues and ultimately respiratory failure， posing a serious threat to human health. To date， the treatment of PF has been a formidable challenge. However， in recent years， with the rise of precision medicine concepts and emerging therapies， the understanding and treatment strategies of PF have been ever advanced. This article provides a comprehensive review of recent research advances in PF within the field of precision medicine， from the perspectives of both molecular biology and genetics， as well as emerging therapeutic strategies， aiming to reveal the potential for tapping into emerging therapeutic strategies using molecular biological tools such as high-throughput bioinformatics technology and analysis. In-depth understanding of these advances can help to better elucidate the pathophysiological processes of PF and provide novel ideas and strategies for future clinical practice， thereby improving patients’ clinical prognosis and quality of life.

Keywords

• pulmonary fibrosis|precision medicine|emerging therapeutic strategy|molecular biology|genetics