Cytokine profile: recent advances in pathogenesis of inflammatory bowel diseases

Abstract

Inflammatory bowel diseases, including ulcerative colitis and Crohn's disease, remain an urgent problem of clinical gastroenterology. Although the etiology of both diseases is still unknown, in recent years progress has been made in studying of pathogenesis of inflammatory processes in patients with inflammatory bowel diseases. In particular, recent data from the foreign literature on the immune dysregulation demonstrate the important roles of novel IL-1 family and the IL-6 family in the inflammatory bowel diseases development, which can determine their diagnostic value and the personalized therapeutic strategy in such patients in the future.