THE ROLE OF ANTIBIOTICS IN TREATING SALIVARY GLAND INFECTIONS

Abstract

Salivary gland infections, called sialadenitis, are mainly caused by bacteria such as Staphylococcus aureus and Streptococcus species, but they can also result from mechanical blockages or viral infections. Complications of untreated or inadequately treated salivary gland infections can be severe, including the formation of abscesses, extension of the infection to neighboring structures, and permanent impairment of salivary gland functionality. In severe cases, surgery may be necessary to drain abscesses or remove obstructions such as salivary stones. Also, in the case of chronic infections, management may include long-term treatments and preventive measures, such as adequate hydration and maintaining rigorous oral hygiene. Integrated management of patients with systemic conditions, such as Sjogren’s syndrome, is crucial for controlling symptoms and preventing complications. Antibiotics work through various mechanisms, including inhibiting bacterial cell wall synthesis, inhibiting protein synthesis, or interfering with essential bacterial functions. The effectiveness of antibiotic treatment is well documented in the medical literature, with clinical trials indicating a significant reduction in symptoms and prevention of severe complications when treatment is administered correctly. For example, bacteria such as Staphylococcus aureus and Streptococcus, commonly involved in salivary gland infections, respond well to antibiotic therapy, which reduces inflammation and associated pain.

Keywords

• sialadenitis
• salivary glands
• antibiotics
• antibiotic resistance
• complications