Journal of Epidemiology (Jan 2021)
Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study
- Atsushi Hozawa,
- Kozo Tanno,
- Naoki Nakaya,
- Tomohiro Nakamura,
- Naho Tsuchiya,
- Takumi Hirata,
- Akira Narita,
- Mana Kogure,
- Kotaro Nochioka,
- Ryohei Sasaki,
- Nobuyuki Takanashi,
- Kotaro Otsuka,
- Kiyomi Sakata,
- Shinichi Kuriyama,
- Masahiro Kikuya,
- Osamu Tanabe,
- Junichi Sugawara,
- Kichiya Suzuki,
- Yoichi Suzuki,
- Eiichi N Kodama,
- Nobuo Fuse,
- Hideyasu Kiyomoto,
- Hiroaki Tomita,
- Akira Uruno,
- Yohei Hamanaka,
- Hirohito Metoki,
- Mami Ishikuro,
- Taku Obara,
- Tomoko Kobayashi,
- Kazuyuki Kitatani,
- Takako Takai-Igarashi,
- Soichi Ogishima,
- Mamoru Satoh,
- Hideki Ohmomo,
- Akito Tsuboi,
- Shinichi Egawa,
- Tadashi Ishii,
- Kiyoshi Ito,
- Sadayoshi Ito,
- Yasuyuki Taki,
- Naoko Minegishi,
- Naoto Ishii,
- Masao Nagasaki,
- Kazuhiko Igarashi,
- Seizo Koshiba,
- Ritsuko Shimizu,
- Gen Tamiya,
- Keiko Nakayama,
- Hozumi Motohashi,
- Jun Yasuda,
- Atsushi Shimizu,
- Tsuyoshi Hachiya,
- Yuh Shiwa,
- Teiji Tominaga,
- Hiroshi Tanaka,
- Kotaro Oyama,
- Ryoichi Tanaka,
- Hiroshi Kawame,
- Akimune Fukushima,
- Yasushi Ishigaki,
- Tomoharu Tokutomi,
- Noriko Osumi,
- Tadao Kobayashi,
- Fuji Nagami,
- Hiroaki Hashizume,
- Tomohiko Arai,
- Yoshio Kawaguchi,
- Shinichi Higuchi,
- Masaki Sakaida,
- Ryujin Endo,
- Satoshi Nishizuka,
- Ichiro Tsuji,
- Jiro Hitomi,
- Motoyuki Nakamura,
- Kuniaki Ogasawara,
- Nobuo Yaegashi,
- Kengo Kinoshita,
- Shigeo Kure,
- Akio Sakai,
- Seiichiro Kobayashi,
- Kenji Sobue,
- Makoto Sasaki,
- Masayuki Yamamoto
Affiliations
- Atsushi Hozawa
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Kozo Tanno
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Naoki Nakaya
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Tomohiro Nakamura
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Naho Tsuchiya
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Takumi Hirata
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Akira Narita
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Mana Kogure
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Kotaro Nochioka
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Ryohei Sasaki
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Nobuyuki Takanashi
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Kotaro Otsuka
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Kiyomi Sakata
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Shinichi Kuriyama
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Masahiro Kikuya
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Osamu Tanabe
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Junichi Sugawara
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Kichiya Suzuki
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Yoichi Suzuki
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Eiichi N Kodama
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Nobuo Fuse
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Hideyasu Kiyomoto
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Hiroaki Tomita
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Akira Uruno
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Yohei Hamanaka
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Hirohito Metoki
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Mami Ishikuro
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Taku Obara
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Tomoko Kobayashi
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Kazuyuki Kitatani
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Takako Takai-Igarashi
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Soichi Ogishima
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Mamoru Satoh
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Hideki Ohmomo
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Akito Tsuboi
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Shinichi Egawa
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Tadashi Ishii
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Kiyoshi Ito
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Sadayoshi Ito
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Yasuyuki Taki
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Naoko Minegishi
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Naoto Ishii
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Masao Nagasaki
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Kazuhiko Igarashi
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Seizo Koshiba
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Ritsuko Shimizu
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Gen Tamiya
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Keiko Nakayama
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Hozumi Motohashi
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Jun Yasuda
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Atsushi Shimizu
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Tsuyoshi Hachiya
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Yuh Shiwa
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Teiji Tominaga
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Hiroshi Tanaka
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Kotaro Oyama
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Ryoichi Tanaka
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Hiroshi Kawame
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Akimune Fukushima
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Yasushi Ishigaki
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Tomoharu Tokutomi
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Noriko Osumi
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Tadao Kobayashi
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Fuji Nagami
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Hiroaki Hashizume
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Tomohiko Arai
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Yoshio Kawaguchi
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Shinichi Higuchi
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Masaki Sakaida
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Ryujin Endo
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Satoshi Nishizuka
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Ichiro Tsuji
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Jiro Hitomi
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Motoyuki Nakamura
- Iwate Medical University, Morioka, Japan
- Kuniaki Ogasawara
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Nobuo Yaegashi
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Kengo Kinoshita
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Shigeo Kure
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- Akio Sakai
- Iwate Medical University, Morioka, Japan
- Seiichiro Kobayashi
- Graduate School of Medicine, Tohoku University, Sendai, Japan
- Kenji Sobue
- Iwate Medical University, Morioka, Japan
- Makoto Sasaki
- Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, Japan
- Masayuki Yamamoto
- Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
- DOI
- https://doi.org/10.2188/jea.JE20190271
- Journal volume & issue
-
Vol. 31,
no. 1
pp. 65 – 76
Abstract
Background: We established a community-based cohort study to assess the long-term impact of the Great East Japan Earthquake on disaster victims and gene-environment interactions on the incidence of major diseases, such as cancer and cardiovascular diseases. Methods: We asked participants to join our cohort in the health check-up settings and assessment center based settings. Inclusion criteria were aged 20 years or over and living in Miyagi or Iwate Prefecture. We obtained information on lifestyle, effect of disaster, blood, and urine information (Type 1 survey), and some detailed measurements (Type 2 survey), such as carotid echography and calcaneal ultrasound bone mineral density. All participants agreed to measure genome information and to distribute their information widely. Results: As a result, 87,865 gave their informed consent to join our study. Participation rate at health check-up site was about 70%. The participants in the Type 1 survey were more likely to have psychological distress than those in the Type 2 survey, and women were more likely to have psychological distress than men. Additionally, coastal residents were more likely to have higher degrees of psychological distress than inland residents, regardless of sex. Conclusion: This cohort comprised a large sample size and it contains information on the natural disaster, genome information, and metabolome information. This cohort also had several detailed measurements. Using this cohort enabled us to clarify the long-term effect of the disaster and also to establish personalized prevention based on genome, metabolome, and other omics information.
Keywords
