International evidence-based guidelines on Point of Care Ultrasound (POCUS) for critically ill neonates and children issued by the POCUS Working Group of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC)
Yogen Singh,
Cecile Tissot,
María V. Fraga,
Nadya Yousef,
Rafael Gonzalez Cortes,
Jorge Lopez,
Joan Sanchez-de-Toledo,
Joe Brierley,
Juan Mayordomo Colunga,
Dusan Raffaj,
Eduardo Da Cruz,
Philippe Durand,
Peter Kenderessy,
Hans-Joerg Lang,
Akira Nishisaki,
Martin C. Kneyber,
Pierre Tissieres,
Thomas W. Conlon,
Daniele De Luca
Affiliations
Yogen Singh
Department of Paediatrics - Neonatology and Paediatric Cardiology, Cambridge University Hospitals and University of Cambridge School of Clinical Medicine
Cecile Tissot
Paediatric Cardiology, Centre de Pédiatrie, Clinique des Grangettes
María V. Fraga
Department of Paediatrics, Children’s Hospital of Philadelphia and Perelman School of Medicine
Nadya Yousef
Division of Paediatrics and Neonatal Critical Care, APHP - Paris Saclay University Hospitals, “A. Béclère” Medical centre
Rafael Gonzalez Cortes
Department of Paediatric Intensive Care, Gregorio Marañón General University Hospital
Jorge Lopez
Department of Paediatric Intensive Care, Gregorio Marañón General University Hospital
Joan Sanchez-de-Toledo
Department of Paediatric Cardiology, Sant Joan de Déu Hospital
Joe Brierley
Department of Paediatric Intensive Care, Great Ormond Street Hospital
Juan Mayordomo Colunga
Department of Paediatric Intensive Care, Hospital Universitario Central de Asturias, Oviedo. CIBER-Enfermedades Respiratorias. Instituto de Salud Carlos III, Madrid. Instituto de Investigación Sanitaria del Principado de Asturias
Dusan Raffaj
Department of Paediatric Intensive Care, Nottingham University Hospitals
Eduardo Da Cruz
Department of Paediatric and Cardiac Intensive Care, Children’s Hospital Colorado
Philippe Durand
Division of Paediatric Critical Care, APHP - Paris Saclay University Hospitals, “Kremlin Bicetre” Medical Centre
Peter Kenderessy
Department of Paediatric Anaesthesia and Intensive Care, Children’s Hospital Banska Bystrica
Hans-Joerg Lang
Department of Paediatrics, Medicins Sans Frontieres (Suisse)
Akira Nishisaki
Department of Anaesthesiology and Critical Care Medicine, Children’s Hospital of Philadelphia and Perelman School of Medicine
Martin C. Kneyber
Department of Paediatrics, Division of Paediatric Critical Care Medicine, Beatrix Children’s Hospital Groningen, University Medical Center Groningen
Pierre Tissieres
Division of Paediatric Critical Care, APHP - Paris Saclay University Hospitals, “Kremlin Bicetre” Medical Centre
Thomas W. Conlon
Department of Anaesthesiology and Critical Care Medicine, Children’s Hospital of Philadelphia and Perelman School of Medicine
Daniele De Luca
Division of Paediatrics and Neonatal Critical Care, APHP - Paris Saclay University Hospitals, “A. Béclère” Medical centre
Abstract Background Point-of-care ultrasound (POCUS) is nowadays an essential tool in critical care. Its role seems more important in neonates and children where other monitoring techniques may be unavailable. POCUS Working Group of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC) aimed to provide evidence-based clinical guidelines for the use of POCUS in critically ill neonates and children. Methods Creation of an international Euro-American panel of paediatric and neonatal intensivists expert in POCUS and systematic review of relevant literature. A literature search was performed, and the level of evidence was assessed according to a GRADE method. Recommendations were developed through discussions managed following a Quaker-based consensus technique and evaluating appropriateness using a modified blind RAND/UCLA voting method. AGREE statement was followed to prepare this document. Results Panellists agreed on 39 out of 41 recommendations for the use of cardiac, lung, vascular, cerebral and abdominal POCUS in critically ill neonates and children. Recommendations were mostly (28 out of 39) based on moderate quality of evidence (B and C). Conclusions Evidence-based guidelines for the use of POCUS in critically ill neonates and children are now available. They will be useful to optimise the use of POCUS, training programs and further research, which are urgently needed given the weak quality of evidence available.