Liver-Derived Systemic Factors Drive β Cell Hyperplasia in Insulin-Resistant States

• Abdelfattah El Ouaamari,
• Dan Kawamori,
• Ercument Dirice,
• Chong Wee Liew,
• Jennifer L. Shadrach,
• Jiang Hu,
• Hitoshi Katsuta,
• Jennifer Hollister-Lock,
• Wei-Jun Qian,
• Amy J. Wagers,
• Rohit N. Kulkarni

Affiliations

Abdelfattah El Ouaamari

Section of Islet Cell Biology and Regenerative Medicine, Joslin Diabetes Center and Harvard Medical School, Boston, MA 02115, USA

Dan Kawamori

Section of Islet Cell Biology and Regenerative Medicine, Joslin Diabetes Center and Harvard Medical School, Boston, MA 02115, USA

Ercument Dirice

Section of Islet Cell Biology and Regenerative Medicine, Joslin Diabetes Center and Harvard Medical School, Boston, MA 02115, USA

Chong Wee Liew

Section of Islet Cell Biology and Regenerative Medicine, Joslin Diabetes Center and Harvard Medical School, Boston, MA 02115, USA

Jennifer L. Shadrach

Section of Islet Cell Biology and Regenerative Medicine, Joslin Diabetes Center and Harvard Medical School, Boston, MA 02115, USA

Jiang Hu

Section of Islet Cell Biology and Regenerative Medicine, Joslin Diabetes Center and Harvard Medical School, Boston, MA 02115, USA

Hitoshi Katsuta

Section of Islet Transplantation and Cell Biology, Joslin Diabetes Center and Harvard Medical School, Boston, MA 02115, USA

Jennifer Hollister-Lock

Section of Islet Transplantation and Cell Biology, Joslin Diabetes Center and Harvard Medical School, Boston, MA 02115, USA

Wei-Jun Qian

Biological Sciences Division and Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA 99352, USA

Amy J. Wagers

Section of Islet Cell Biology and Regenerative Medicine, Joslin Diabetes Center and Harvard Medical School, Boston, MA 02115, USA

Rohit N. Kulkarni

Section of Islet Cell Biology and Regenerative Medicine, Joslin Diabetes Center and Harvard Medical School, Boston, MA 02115, USA