Role of genetic factors (biology of telomeres) in cardiac rehabilitation

Abstract

Cardiac rehabilitation (CR) is one of the effective healthcare types for cardiovascular patients. At the same time, the choice of the most effective CR methods for a particular patient remains a problem. An increasing number of studies are devoted to the application of genetic methods for studying human health. Particular attention is drawn to determining the telomere length. The review purpose was to analyze the literature on various studies on the significance of assessing the chromosome telomeres for characterizing human health and choosing effective CR methods. The article discusses issues related to the relationship between the telomere length and cardiovascular risk factors, dietary pattern, and psychological status of a person. We also assessed the effectiveness of various exercise types at the genetic level. In preparing the review, publications over the past 14 years were searched in the MEDLINE/PubMed, Scopus, Cochrane Library, PEDro, eLIBRARY, and Google Scholar databases. The presented facts indicate the need for further study and effective use of one of the genetic factors protecting chromosome telomeres in CR.

Keywords

• telomeres
• telomerase
• cardiovascular risk factors
• cardiac rehabilitation
• physical training