Communications Biology (Aug 2022)

FACT modulates the conformations of histone H2A and H2B N-terminal tails within nucleosomes

  • Yasuo Tsunaka,
  • Hideaki Ohtomo,
  • Yoshifumi Nishimura

DOI
https://doi.org/10.1038/s42003-022-03785-z
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 14

Abstract

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NMR experiments reveal distinct interactions of the histone chaperone, FACT, with the proximal and distal flexible histone H2A and H2B tails of the asymmetrically unwrapped nucleosome.