Electrocardiographic and other Noninvasive Hemodynamic Markers in Decompensated CHF Patients

Abstract

Acutely decompensated chronic heart failure (adCHF) is among the most important causes of in-hospital mortality. R-wave peak time (RpT) or delayed intrinsicoid deflection was proposed as a risk marker of sudden cardiac death and heart failure decompensation. Authors want to verify if QR interval or RpT, obtained from 12-lead standard ECG and during 5-min ECG recordings (II lead), could be useful to identify adCHF. At hospital admission, patients underwent 5-min ECG recordings, obtaining mean and standard deviation (SD) of the following ECG intervals: QR, QRS, QT, JT, and T peak–T end (Te). The RpT from a standard ECG was calculated. Patients were grouped by the age-stratified Januzzi NT-proBNP cut-off. A total of 140 patients with suspected adCHF were enrolled: 87 (mean age 83 ± 10, M/F 38/49) with and 53 (mean age: 83 ± 9, M/F: 23/30) without adCHF. V5-, V6- (p pT, and QRSD, QRSSD, QTSD, JTSD, and TeSDp p p 6 RpT was directly related to NT-proBNP (r: 0.26, p p 5-6 and QRSD) could be used as a possible marker of adCHF.

Keywords

• acutely decompensated chronic heart failure
• intrinsicoid deflection time
• ECG markers
• tele-monitoring
• prevention