Pulmonary and coronary arterial abnormalities in patients with IgG4-related disease

Rory L. Cochran, MD, PhD; Holly R. Brideau, MD, MS; Markus Y. Wu, MD; John H. Stone, MD, MPH; Zachary S. Wallace, MD, MSc; Brent P. Little, MD

Radiology Case Reports (Dec 2022)

Pulmonary and coronary arterial abnormalities in patients with IgG4-related disease

Rory L. Cochran, MD, PhD,
Holly R. Brideau, MD, MS,
Markus Y. Wu, MD,
John H. Stone, MD, MPH,
Zachary S. Wallace, MD, MSc,
Brent P. Little, MD

Affiliations

Rory L. Cochran, MD, PhD: Department of Radiology, Massachusetts General Hospital, 55 Fruit St, Boston, MA, USA
Holly R. Brideau, MD, MS: Department of Radiology, Massachusetts General Hospital, 55 Fruit St, Boston, MA, USA
Markus Y. Wu, MD: Department of Radiology, Massachusetts General Hospital, 55 Fruit St, Boston, MA, USA
John H. Stone, MD, MPH: Division of Rheumatology, Department of Medicine, Massachusetts General Hospital, 55 Fruit St, Boston, MA, USA
Zachary S. Wallace, MD, MSc: Division of Rheumatology, Department of Medicine, Massachusetts General Hospital, 55 Fruit St, Boston, MA, USA
Brent P. Little, MD: Department of Radiology, Massachusetts General Hospital, 55 Fruit St, Boston, MA, USA; Department of Radiology, Mayo Clinic Florida, 4500 San Pablo Rd, Jacksonville, FL 32224, USA; Corresponding author.

Journal volume & issue: Vol. 17, no. 12
pp. 4924 – 4927

Abstract

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IgG4-related disease (IgG4-RD) is an immune-mediated multiorgan fibroinflammatory disorder with variable clinical presentations. IgG4-RD cardiovascular involvement is considered rare, with pulmonary arterial involvement reported in a small subset of cases. Known pulmonary artery manifestations include pulmonary arteritis, pulmonary artery stenoses and central pulmonary artery aneurysms. Here we report 2 different patients with multifocal dilatation of the segmental and subsegmental pulmonary arteries with differing degrees of severity. Both patients also had coronary arterial abnormalities.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: http://www.journals.elsevier.com/radiology-case-reports/

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Abstract

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