Radiology Case Reports (Dec 2022)

Pulmonary and coronary arterial abnormalities in patients with IgG4-related disease

  • Rory L. Cochran, MD, PhD,
  • Holly R. Brideau, MD, MS,
  • Markus Y. Wu, MD,
  • John H. Stone, MD, MPH,
  • Zachary S. Wallace, MD, MSc,
  • Brent P. Little, MD

Journal volume & issue
Vol. 17, no. 12
pp. 4924 – 4927

Abstract

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IgG4-related disease (IgG4-RD) is an immune-mediated multiorgan fibroinflammatory disorder with variable clinical presentations. IgG4-RD cardiovascular involvement is considered rare, with pulmonary arterial involvement reported in a small subset of cases. Known pulmonary artery manifestations include pulmonary arteritis, pulmonary artery stenoses and central pulmonary artery aneurysms. Here we report 2 different patients with multifocal dilatation of the segmental and subsegmental pulmonary arteries with differing degrees of severity. Both patients also had coronary arterial abnormalities.

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