Study of various Physiological, Biochemical and Hematological parameters in Repeated Blood Donors

Abstract

Background: Blood donation is a humanitarian act to save the lives of sick and needy patients. Repeated blood donation can have some adverse effects on overall health of repeated blood donors. Objective: To evaluate cardiovascular, respiratory and lipid profiles and study the effects of repeated blood donation among repeated blood donors. To compare these parameters with persons who never donated blood. Method: A Hospital based, comparative, cross sectional study was conducted. Twenty males, who donated blood every three months in a year were compared against 20 age matched males who never donated blood in last one year as well as they were never been the repeated blood donors before that. Results: The weight (Wt), heart rate (HR), systolic blood pressure (SBP), respiratory rate (RR), peak expiratory flow rate (PEFR), chest expansion (CE), hemoglobin (Hb), packed cell volume (PCV), red blood cell count (RBC), and high density lipoproteins (HDL) were significantly lower among repeated blood donors compared to non donors. Whereas erythrocyte sedimentation rate (ESR) was significantly higher among repeated blood donors compared to non donors. Conclusion: Thus out of 25 parameters studied, 11 were found to be statistically significant. Out of these 11 parameters, Wt, PEFR, CE, Hb, PCV, RBC, and ESR have lower values and ESR and HDL has higher value and is adverse for the health of the repeated blood donors. On the other hand, HR, SBP, and RR lower values may be beneficial for them.

Keywords

• blood donation
• lipid profile
• repeated blood donors