Nature Communications (Jun 2022)

Altered predictive control during memory suppression in PTSD

  • Giovanni Leone,
  • Charlotte Postel,
  • Alison Mary,
  • Florence Fraisse,
  • Thomas Vallée,
  • Fausto Viader,
  • Vincent de La Sayette,
  • Denis Peschanski,
  • Jaques Dayan,
  • Francis Eustache,
  • Pierre Gagnepain

DOI
https://doi.org/10.1038/s41467-022-30855-x
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 16

Abstract

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It remains unclear how predictions of future threat affect memory recall, specifically in the case of post-traumatic stress disorder (PTSD). Here, the authors combined computational modeling and brain connectivity analyses to show that individuals with PTSD have exaggerated predictive control and reduced reactive control in a memory suppression task.