Fatal Balamuthia mandrillaris brain infection associated with improper nasal lavage

Abstract

We report the case of a 69-year-old female who presented with a chronic nasal skin rash, new onset focal seizure, and a cerebral ring-enhancing lesion after a year of improper nasal irrigation. Despite aggressive and novel anti-amoebic treatment, she died as a result of a Balamuthia mandrillaris brain infection. Keywords: Amoeba, Balamuthia mandrillaris, Infectious encephalitis, Amoebic encephalitis, Nasal lavage