Action of chondroitin sulfate on the glutathione system in blood serum at carrageenan-induced acute inflammation

Abstract

Increase of content of oxidized glutathione (GSSG) is fixed in blood serum at carrageenan-induced rat paw inflammation, as well as increase of the glutathione transferase activity. Upon the same experimental conditions, the level of reduced glutathione (GSH) and activity of glutathione peroxidase and glutathione reductase were decreased. All above mentioned indices was closer to control values in animals treated simultaneously with сarrageenan and drug on the basis of chondroitin sulfate.

Keywords

• acute paw inflammation
• chondroitin sulfate
• glutathione system
• blood serum